Repository of Research and Investigative Information

Repository of Research and Investigative Information

Dezful University of Medical Sciences

Prevalence and determinants of diabetes and prediabetes in southwestern Iran: the Khuzestan comprehensive health study (KCHS)

(2021) Prevalence and determinants of diabetes and prediabetes in southwestern Iran: the Khuzestan comprehensive health study (KCHS). Bmc Endocrine Disorders. p. 11.

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Official URL: <Go to ISI>://WOS:000671192400002


BackgroundThe Middle East and North Africa (MENA) is postulated to have the highest increase in the prevalence of diabetes by 2030; however, studies on the epidemiology of diabetes are rather limited across the region, including in Iran.MethodsThis study was conducted between 2016 and 2018 among Iranian adults aged 20 to 65years residing in Khuzestan province, southwestern Iran. Diabetes was defined as the fasting blood glucose (FBG) level of 126mg/dl or higher, and/or taking antidiabetic medications, and/or self-declared diabetes. Prediabetes was defined as FBG 100 to 125mg/dl. Multinomial logistic regression models were used to examine the association of multiple risk factors that attained significance on the outcome.ResultsOverall, 30,498 participants were recruited; the mean (SD) age was 41.6 (+/- 11.9) years. The prevalence of prediabetes and diabetes were 30.8 and 15.3, respectively. We found a similar prevalence of diabetes in both sexes, although it was higher among illiterates, urban residents, married people, and smokers. Participants aged 50-65 and those with Body Mass Index (BMI) 30kg/m(2) or higher were more likely to be affected by diabetes RR: 20.5 (18.1,23.3) and 3.2 (3.0,3.6). Hypertension RR: 5.1 (4.7,5.5), waist circumference (WC) equal or more than 90cm RR: 3.6 (3.3,3.9), and family history RR: 2.3 (2.2,2.5) were also significantly associated with diabetes. For prediabetes, the main risk factors were age 50 to 65years RR: 2.6 (2.4,2.8), BMI 30kg/m(2) or higher RR: 1.9 (1.8,2.0), hypertension and WC of 90cm or higher RR: 1.7 (1.6,1.8). The adjusted relative risks for all variables were higher in females than males, with the exception of family history for both conditions and waist circumference for prediabetes.Conclusions Prediabetes and diabetes are prevalent in southwestern Iran. The major determinants are older age, obesity, and the presence of hypertension. Further interventions are required to escalate diabetes prevention and diagnosis in high-risk areas across Iran.

Item Type: Article
Keywords: Diabetes Prediabetes Epidemiology Risk-factors Low and middle-income countries Middle-east Iran risk-factors gender-differences blood-pressure type-2 mellitus population adults care epidemiology tehran Endocrinology & Metabolism
Page Range: p. 11
Journal or Publication Title: Bmc Endocrine Disorders
Journal Index: ISI
Volume: 21
Number: 1
Identification Number:
Depositing User: مهندس مهدی شریفی

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