Repository of Research and Investigative Information

Repository of Research and Investigative Information

Dezful University of Medical Sciences

The effect of Bilineaster “Cotoneaster” on reducing bilirubin in neonates with jaundice -a triple-blind randomized clinical trial

(2021) The effect of Bilineaster “Cotoneaster” on reducing bilirubin in neonates with jaundice -a triple-blind randomized clinical trial. Journal of Advanced Pharmacy Education and Research. pp. 23-28. ISSN 22493379 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Introduction: Jaundice is one of the most common concerns in neonates. In Iran, the extract of Cotoneaster frigidus is used to reduce physiologic jaundice according to traditional medicines. This study aimed to investigate the effect of medication “Bilineaster” on the reduction of jaundice in neonates. Materials and Methods: This study was a randomized, triple-blind clinical trial. In this study, 96 neonates with physiologic jaundice referred to a pediatric clinic in Dezful were selected by the available sampling method. After assessing the required laboratory tests, they were randomly allocated into the case and control groups. In this study, in addition to phototherapy, Cotoneaster frigidus extract and placebo were administered to the case and control groups, respectively, and the level of bilirubin was checked every 24 hours for 72 hours after initiation of treatment. The gathered data were analyzed using the chi-square test, independent t-test, and ANOVA by SPSS software. Results: There was no significant difference between the experimental and control groups regarding gender, age, birth weight, hemoglobin level, type of delivery, G6PD enzyme, and total bilirubin level at baseline (p>0.05). The analysis of variance with repeated measures showed that there was a significant difference in serum bilirubin levels between the two groups at 48 and 72 hours after initiation of the treatment (p≤0.0S). Conclusions: This study indicated that the consumption of Bilineaster drop is effective in the reduction of bilirubin serum levels in neonates. © 2021. Journal of Advanced Pharmacy Education & Research | Published by SPER Publication.

Item Type: Article
Keywords: Cotoneaster frigidus Herbal Medicine Iranian Medicine Jaundice Neonates
Subjects: WS Pediatrics > WS 200-342 Diseases of Children and Adolescents
WS Pediatrics > WS 360-368 Pediatric Specialties
Divisions: Education Vice-Chancellor Department > Faculty of Nursing and Midwifery > Department of Pediatric Nursing
Page Range: pp. 23-28
Journal or Publication Title: Journal of Advanced Pharmacy Education and Research
Journal Index: Scopus
Volume: 11
Number: 1
Identification Number: https://doi.org/10.51847/QABGSKL
ISSN: 22493379 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.dums.ac.ir/id/eprint/770

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