Repository of Research and Investigative Information

Repository of Research and Investigative Information

Dezful University of Medical Sciences

Level of Bisphenol A in Follicular Fluid and Serum and Oocyte Morphology in Patients Undergoing IVF Treatment

(2019) Level of Bisphenol A in Follicular Fluid and Serum and Oocyte Morphology in Patients Undergoing IVF Treatment. Journal of family & reproductive health. pp. 154-159. ISSN 1735-8949 (Print) 1735-9392 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/32201490

Abstract

Objective: To assess the correlation between the levels of BPA in the serum and follicular fluid (FF) using oocyte morphology. Materials and methods: In this cross-sectional research, oocyte, FF, and serum samples were obtained from a sample population consisting of 90 women undergone in vitro fertilization in Ganjavian Hospital in Dezful, Iran during October 2017-March 2018. The ELISA kit was utilized for the measurement of the BPA levels. In addition, oocyte morphology simultaneous with inverted optical microscopy. Results: Follicular fluid BPA levels had no significant effect on MII oocytes (p >/= 0.05). However, the mean levels of degenerated oocytes and germinal vesicle (GV) were significantly higher in the women with high BPA levels in the FF (p </= 0.05). Moreover, the mean counts of MII oocytes and oocytes were significantly higher in the women with serum BPA levels of </= 50 ng/ml (p </= 0.05), while the mean count of GV oocytes was significantly higher in the women with serum BPA levels of >/= 150 ng/ml (p </= 0.05). Conclusion: According to the results, higher FF BPA levels were associated with the higher counts of GVs and oocytes, while oocytes with higher maturity can be achieved in lower levels of BPA in the serum of patients.

Item Type: Article
Keywords: Bisphenol A Follicular Fluid Ivf Oocyte Morphology
Subjects: QS Human Anatomy > QS504-532 Histology
WP Gynecology and Obstetrics > WP 565-570 Fertility. Infertility
Divisions: Education Vice-Chancellor Department > Faculty of Medicine > Departments of Clinical Sciences > Department of Obstetrics and Gynecology
Page Range: pp. 154-159
Journal or Publication Title: Journal of family & reproductive health
Journal Index: Pubmed
Volume: 13
Number: 3
ISSN: 1735-8949 (Print) 1735-9392 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.dums.ac.ir/id/eprint/650

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