Repository of Research and Investigative Information

Repository of Research and Investigative Information

Dezful University of Medical Sciences

Anti-Candida activity of Curcumin: A review

(2020) Anti-Candida activity of Curcumin: A review. Current drug discovery technologies. ISSN 1875-6220 (Electronic) 1570-1638 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/32418527

Abstract

Curcumin is one of the important natural compounds that is extracted from turmeric. This compound and its derivatives have numerous biological properties, including antioxidant, anticancer, anti-inflammatory, antimicrobial and healing effects. Extensive research in various fields has been conducted on turmeric as it is widely used as a food additive. The significant antifungal activity is one of the major effects of curcumin. In this paper, recent studies on the effects of different forms of curcumin drug on the candidiasis were systematically examined and discussed. The data in this study were extracted from the articles and reports published in the Web of Science, Google Scholar, PubMed, and Scopus databases. After the preliminary investigation, relevant reports were selected and classified based on the incorporated formulation and purpose of the study. After a systematic discussion of the data, it was found that the use of medicinal forms based on nanoparticles can increase the absorption and target the controlled release of curcumin with a more effective role compared to other formulations. Consequently, it can be concluded that new methods of modern medicine can be employed to increase the efficacy of natural pharmaceutical compounds used in the past. In this regard, the present study analyzed the effect of curcumin against various Candida infections using the recent data. It was found that applying a combination of drug formulation or the formulation of curcumin and its derivatives can be an effective strategy to overcome the medicine resistance in fungal infections, especially candidiasis.

Item Type: Article
Keywords: Candida Curcumin Medicinal plant fungi herbal medicine mycology
Subjects: QW Microbiology and Immunology > QW 501-949 Immunology
Divisions: Education Vice-Chancellor Department > Faculty of Medicine > Department of Basic Science > Immunology Department
Journal or Publication Title: Current drug discovery technologies
Journal Index: Pubmed
Identification Number: https://doi.org/10.2174/1570163817666200518074629
ISSN: 1875-6220 (Electronic) 1570-1638 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.dums.ac.ir/id/eprint/644

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