Repository of Research and Investigative Information

Repository of Research and Investigative Information

Dezful University of Medical Sciences

Comparison of 6 weeks of high intensity interval training and continuous training on Desnutrin, Adiponectin and Adiponectin Receptor1 genes expression in two subcutaneous adipose tissue and quadriceps muscle tissue of obese male rats

(2019) Comparison of 6 weeks of high intensity interval training and continuous training on Desnutrin, Adiponectin and Adiponectin Receptor1 genes expression in two subcutaneous adipose tissue and quadriceps muscle tissue of obese male rats. Medical Science. pp. 700-709. ISSN 2321-7359

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Abstract

Background: Obesity disrupts the regulation of desnutrin, adiponectin and AdipoR1. The purpose of the present study was to compare 6 weeks of HIIT and continuous training on the expression of desnutrin, adiponectin and Adipo R1 genes in two subcutaneous adipose tissues and quadriceps muscle tissue in obese male rats. Methods. 30 obese Wistar rats were randomly divided into 3 groups: control (n=10), continuous Training (n=10) and HIIT (n=10). Continuous training and HIIT were performed 6 weeks and 6 sessions per week. Forty-eight hours after the last training session, the adipose tissue and muscle tissue were extracted, and the expression level was assessed using the RT-PCR method. Results. The results of showed that there was a significant difference in the expression of desnutrin (P=0.011) and adiponectin genes (P=0.040) in the adipose tissue between the continuous training and HIIT groups. However, the expression of desnutrin (P=0.855) and Adipo R1 genes (P=0.565) of the muscle tissue was not significant between the two groups. Conclusions. It was found in the adipose tissue, continuous training has a greater effect on the expression of Desnutrin and Adiponectin genes than HIIT. However, in the muscle tissue, there is no difference between the HIIT and continuous training in the expression of Desnutrin and AdipoR1 genes. for weight loss HIIT is a better way.

Item Type: Article
Keywords: Obesity subcutaneous adipose tissues quadriceps muscle tissue Continuous training High intensity interval training skeletal-muscle increases insulin oxidation Research & Experimental Medicine
Page Range: pp. 700-709
Journal or Publication Title: Medical Science
Journal Index: ISI
Volume: 23
Number: 99
ISSN: 2321-7359
Depositing User: مهندس مهدی شریفی
URI: http://eprints.dums.ac.ir/id/eprint/5

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