Repository of Research and Investigative Information

Repository of Research and Investigative Information

Dezful University of Medical Sciences

The effect of celery (Apium graveolens L.) on fertility: A systematic review

(2017) The effect of celery (Apium graveolens L.) on fertility: A systematic review. Journal of complementary & integrative medicine. ISSN 1553-3840 (Electronic) 1553-3840 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/28985183

Abstract

Background Fertility and infertility problems are among the complex issues in medicine. The use of herbal products in the treatment of fertility has been considered as an alternative to synthetic drugs. Celery containing known compounds can have an impact on the fertility rate. The aim of this study was to do a systematic review on conducted studies in conjunction with the celery and reproduction. Methods Required papers were searched from databases like Science direct, PubMed, Scopus, and Springer. Keywords used in this study were "Apium graveolens L.", "fertility", "reproductive system", "sperm", "testis", "delivery", "sexual hormone", "LH", "FSH", "testosterone", "semen", "male", and "female". Out of 238 collected articles (published in the period 1995 to 2015), 222 were excluded due to non-relevance and lack of access to the original article. Results The notable points were the different results seen by different researchers during different treatment periods or at different doses. Of the 16 studies reviewed in this study, 13 studies have mentioned the positive effect of celery on fertility, while three studies reported the inhibitory effects of this plant. Conclusions Celery can have protective effects against substances such as sodium valproate, propylene glycol, and diethyl phthalate causing damages to the testicular structure and spermatogenesis. In this regard, the doses used and the treatment time while using the plant must be accurately investigated. Since there are compounds such as apigenin, the celery can induce inhibitory effects on fertility in case of chronic use or high concentration.

Item Type: Article
Keywords: *Apium Female Fertility/*drug effects Humans Infertility/chemically induced/*prevention & control Male *Plant Extracts/pharmacology/therapeutic use Protective Agents/pharmacology/therapeutic use Spermatogenesis/drug effects Testis/drug effects Apium graveolens L. fertility reproductive
Journal or Publication Title: Journal of complementary & integrative medicine
Journal Index: Pubmed
Volume: 15
Number: 2
Identification Number: https://doi.org/10.1515/jcim-2016-0141
ISSN: 1553-3840 (Electronic) 1553-3840 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.dums.ac.ir/id/eprint/388

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