Repository of Research and Investigative Information

Repository of Research and Investigative Information

Dezful University of Medical Sciences

THERAPEUTIC EFFECTS OF HERBS ON MYCOBACTERIUM TUBERCULOSIS: A SYSTEMATIC REVIEW

(2017) THERAPEUTIC EFFECTS OF HERBS ON MYCOBACTERIUM TUBERCULOSIS: A SYSTEMATIC REVIEW. International Journal of Health Medicine and Current Research-Ijhmcr. pp. 627-640. ISSN 2528-4398

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Abstract

Mycobacterium tuberculosis is one of the agents responsible for tuberculosis in human and animals. This bacterium damages the lungs, central nervous system, lymphatic system, and blood circulating system. The aim of this study was to provide information about the herbs which are effective on Mycobacterium tuberculosis. In order to gather the information, keywords of "extract", "plants" and "Mycobacterium tuberculosis" were searched in scientific databases including ScienceDirect, Pubmed, Scopus, Medline, SID, Iranmedex, and Medlib. In vivo and in vitro studies were included. 380 articles were collected in general. After exclusion of non-relevant and repetitive articles, 24 herbs were studied in this review. Effective herbs have shown their antibacterial effects through mechanisms such as increasing inflammatory cytokines like IFN-gamma, IL-12, regulating the balance between Th1/Th2 and leading this ratio toward Th1, disturbing transcription from SP1 gene in promoter region of TACO regulatory gene and decreasing its expression, disturbing the ion balance in bacterial membrane and forming pores in the two-plants could provide scientists who work on medicine and treatment with useful information.

Item Type: Article
Keywords: Tuberculosis Drug resistance Natural products Inflammation ent-kaurane diterpenoids antimycobacterial activity in-vitro indoloquinazoline alkaloids evodia-rutaecarpa medicinal-plants drug-resistance mentha-spicata lantana-camara essential oils Health Care Sciences & Services
Page Range: pp. 627-640
Journal or Publication Title: International Journal of Health Medicine and Current Research-Ijhmcr
Journal Index: ISI
Volume: 2
Number: 4
Identification Number: https://doi.org/10.22301/ijhmcr.2528-3189.627
ISSN: 2528-4398
Depositing User: مهندس مهدی شریفی
URI: http://eprints.dums.ac.ir/id/eprint/222

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